PGx Testing
States are tied to adverse drug reactions
Better understanding how patients will respond to medications
Genetics account for 20–90% of variability in drug disposition and effects. The rate of drug metabolism varies between individuals. People can be poor, intermediate, extensive or rapid metabolizer of drugs based on their genotype for CYP 450 family of enzymes. CYP 450 family of enzymes metabolized drugs to active or inactive metabolites. People that are poor or rapid metabolizer are prone to drug toxicity or lower effectiveness of drugs.
Our pharmacogenetic testing service, PGx Testing, uses a patient’s genes to determine how they will re spond to a particular medicine or a combination of medicines and identifies their unique sensitivities to possible drug effects. As a result, healthcare providers can minimize or completely avoid trial-and-error dosing and substantially reduce the risk of potential adverse drug events.
770,000 injuries and deaths annually in the United.
Drugs Influenced By Genetic Variation
- Cardiovascular ACE Inhibitors, Antiarrhythmics, Anticoagulants, Antiplatelets, Beta Blockers, Statins
- Gastroenterology Proton-Pump Inhibitors
- Immunology Calcineurin Inhibitors, Immunosuppresants
- Infectious Disease Antivirals, Antibiotics, Antimalarials, Antifungals
- Neurology Anticonvulsants
- Oncology 5-HT3 Antagonists, Antineoplastic
Simple, Accurate and Beneficial
- This potentially life-saving test is simple and accurate.
- Our expeditious 2- to 10-day turnaround time significantly outpaces the drawn out 6-week timeframe by many labs.
- The comprehensive results and report are easy to understand for both clinicians and patients.
- PGx test findings eliminate guesswork for physicians.
- Patient safety is significantly improved. • Treatment selection is optimized.
- Claims are typically pre-adjudicated to ensure insurance coverage, and a compet itive cash pricing option is also available.
Physicians frequently utilize PGx test ing when a patient has one or more of these issues:
- an efficacious medication has been difficult to pinpoint
- an unusually high dosage is required
- an odd or expensive regimen has been prescribed previously
- a family history of ADRs exists
- a new medication is required
- a prescription for Plavix (Clopidogrel) will be initiated
- a drug metabolized by the CYP450 enzyme is being taken
- a drug that inhibits or stimulates CYP
- 450 enzyme is taken
- Multiple prescription medications are being taken Agents, Estrogen Modulators, Platinum Compounds, Purine Analogs, Pyrimidine Analogs
- Pain Management Nonsteroidal Antinflammatory Drugs (NSAIDs), Opioids
- Psychiatry Antipsychotics, Benzodiazepines, Selective Serotonin Reuptake Inhibitors (SSRIs), Tricyclic Antidepressants
Important Questions
Frequently Asked Questions
Have a question? You might find the answer below in our FAQs!
Who can use Simplicity Diagnostics?
Simplicity Diagnostics works with physicians, medical practices, clinics, hospitals, and other healthcare organizations.
How do I become a provider?
Getting started is simple. Complete our Become a Provider form, and our team will contact you to help with enrollment and next steps.
What types of testing do you offer?
We offer a range of diagnostic and specialty testing, including genetic and genomic testing, pharmacogenomics (PGx), oncology-related testing, metabolic testing, immunology, toxicology, and other specialty laboratory services.
How quickly will we receive results?
Many tests have a typical turnaround time of 24–48 hours, although turnaround times vary depending on the specific test and specimen requirements.
How do I order a test?
Once your practice is set up as a provider, our team will provide the information and resources needed to order testing and submit specimens.
How are test results delivered?
Test results are delivered securely through our provider workflow. Our team can help your practice understand the process and access results.
Can your team help our office choose the right test?
Yes. If your practice has questions about test selection, specimen requirements, ordering, or other laboratory-related needs, our provider support team is available to assist.
What specimen types do you accept?
Specimen requirements vary by test. Please refer to the specific test information or contact our provider support team before collecting or shipping a specimen.
Do you work with insurance?
Insurance coverage and patient responsibility can vary by test, patient, and plan. Our team can provide information about the billing process and available options.
Can I speak with someone about setting up my practice?
Absolutely. Contact our team and we can walk your practice through the process of becoming a Simplicity Diagnostics provider.
Why should my practice choose Simplicity Diagnostics?
We focus on making laboratory testing simple for healthcare providers through reliable testing, fast turnaround times, a broad test menu, and responsive provider support.
How do I get started?
The first step is simple: Become a Simplicity Diagnostics provider.
