CGx Testing
Understand your patients’ risk factors for cancer using the power of genetics
GenviewDX’s CGx Testing targets the most important genes associated with breast, colon, pancreatic, gynecological and mela noma cancers. These tests are ordered frequently by oncologists, as well as family doctors and internal medicine doctors that are primary care physicians and with patients with at-risk family histories.
Inherited Gene Mutations
GenviewDX offers a multi-gene panel that accurately identifies the presence of an inherited gene mutation or alteration. A pa tient who receives a negative test result will benefit from peace of mind knowing they did not inherit a harmful gene variant, while a patient who receives a positive test result will benefit from opportunities to better understand and potentially manage their cancer risk, and to make important decisions about their medical care.
In addition to determining an increased risk for developing cancer, our blood panel also points to types of cancer screenings that should be conducted.
While many inherited genetic variants are beneficial or neutral, others are harmful and believed to contribute to 5-10% of all cancers.
Breast and Ovarian Cancer
BRCA genes come in pairs (BRCA1 and BRCA2). Only one gene in the pair needs to have a mutation to put a patient at risk for cancer. For women, a BRCA muta tion increases the risk for breast and ovarian cancers. For men, the overall risk for cancer is lower than women, although the risk for breast, prostate and skin cancers is increased.
Lynch Syndrome
Inherited mutations in the genes of MLH1, MSH2, MSH6, PMS2 and EPCAM give a patient an increased lifetime risk of certain cancers. This genetic syndrome, known as Lynch syndrome and also called hereditary non-polyposis colorectal cancer (HNPCC), puts patients at a higher risk of certain types of cancer.
Who and Why to Test
The American Cancer Society has outlined certain factors associated with cancers that run in families. Physicians should con sider CGx testing for any patient who has one or more of these family histories.
- Multiple cases of the same type of cancer, particularly if it is a rare or uncommon type of cancer
- Cancers occurring at younger-than-usual ages, such as col orectal cancer in a 22-year-old
- More than one type of cancer occurring in one family mem ber, such as a female with both breast and ovarian cancer
- Cancers occurring in both of a pair of organs, such as both breasts, both kidneys, both eyes, both ovaries
- Cancer occurring in a gender not usually affected, such as breast cancer in a male relative
- Cancer occurring across generations, such as grandmother, mother and daughter, or grandfather, father and son
- Childhood cancer occurring in more than one sibling, such as sarcoma in both a sister and brother
Genes List
- BRCA1
- MUTYH
- BRCA2
- SMAD4
- APC
- ATM
- BLM
- NF1
- GJB2
- COL1A1
- GJB6
- FBN1
- KIT
- BMPR1A
- MLH1
- POLE
- MSH2
- CDK4
- MSH6
- GREM1
- PALB2
- RAD51D
- PMS2
- BRIP1
- PTEN
- RAD51C
- TERT
- POLD1
- TP53
- BARD1
- EPCAM
- CHEK2
- CDKN2A
- MITF
- STK11
- BAP1
- CDH1
- NBN
Important Questions
Frequently Asked Questions
Have a question? You might find the answer below in our FAQs!
Who can use Simplicity Diagnostics?
Simplicity Diagnostics works with physicians, medical practices, clinics, hospitals, and other healthcare organizations.
How do I become a provider?
Getting started is simple. Complete our Become a Provider form, and our team will contact you to help with enrollment and next steps.
What types of testing do you offer?
We offer a range of diagnostic and specialty testing, including genetic and genomic testing, pharmacogenomics (PGx), oncology-related testing, metabolic testing, immunology, toxicology, and other specialty laboratory services.
How quickly will we receive results?
Many tests have a typical turnaround time of 24–48 hours, although turnaround times vary depending on the specific test and specimen requirements.
How do I order a test?
Once your practice is set up as a provider, our team will provide the information and resources needed to order testing and submit specimens.
How are test results delivered?
Test results are delivered securely through our provider workflow. Our team can help your practice understand the process and access results.
Can your team help our office choose the right test?
Yes. If your practice has questions about test selection, specimen requirements, ordering, or other laboratory-related needs, our provider support team is available to assist.
What specimen types do you accept?
Specimen requirements vary by test. Please refer to the specific test information or contact our provider support team before collecting or shipping a specimen.
Do you work with insurance?
Insurance coverage and patient responsibility can vary by test, patient, and plan. Our team can provide information about the billing process and available options.
Can I speak with someone about setting up my practice?
Absolutely. Contact our team and we can walk your practice through the process of becoming a Simplicity Diagnostics provider.
Why should my practice choose Simplicity Diagnostics?
We focus on making laboratory testing simple for healthcare providers through reliable testing, fast turnaround times, a broad test menu, and responsive provider support.
How do I get started?
The first step is simple: Become a Simplicity Diagnostics provider.
